Bladder Urothelium Articles

Articles

Beyond the Abstract - The mechanoreceptor TRPV4 is localized in adherence junctions of the human bladder urothelium: A morphological study, by Dick AW Janssen

BERKELEY, CA (UroToday.com) - This published abstract concerns the sensory function of transient receptor potential vanilloid subtype 4 (TRPV4) in the human bladder.

Published December 8, 2011
Differential Expression of ROMK and KCNQ1 Potassium Channels in Bladder Urothelium of Patients with Interstitial Cystitis/Painful Bladder Syndrome.

To investigate the changes including expression and localization of two potassium channels, renal outer medullary K(+) channel (ROMK) and voltage-gated K(+) channel 7.1 (KCNQ1), after increased urinary potassium leakage in patients with interstitial cystitis/painful bladder syndrome (IC/PBS).
Published November 30, 2016
Impaired Na(+)/K(+)-ATPase Function in Patients with Interstitial Cystitis/Painful Bladder Syndrome.

Na(+)/K(+)-ATPase (NKA) is abundantly expressed in the basolateral membrane of epithelial cells, which is necessary for tight junction formation. The tight junction is an urothelial barrier between urine and the underlying bladder.

Published February 8, 2016