BJUI Mini Reviews - Urothelial lesions with inverted growth patterns: histogenesis, molecular genetic findings,differential diagnosis and clinical management

BERKELEY, CA (UroToday.com) - A number of well-recognized urothelial lesions with inverted morphology occur in the urinary bladder.

Some are so common that they are considered normal variants of urothelium, whereas others are rare. It is important for the surgical pathologist to recognize these lesions and their overlapping morphological features, because in some cases establishing an accurate diagnosis is challenging. In this article, we review the spectrum of inverted urothelial lesions of the bladder. Emphasis is placed on differential diagnosis, molecular genetic findings, morphology and histogenesis....View or save the Mini Review as a .pdf file

 


Kurt B. Hodges,* Antonio Lopez-Beltran, Gregory T. MacLennan, Rodolfo Montironi,§ and Liang Cheng*,¶

* Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, Department of Pathology, Case Western Reserve University, Cleveland, OH, Department of Urology, Indiana University School of Medicine, Indianapolis, IN, USA, Department of Pathology, Cordoba University, Cordoba, Spain, and § Institute of Pathological Anatomy and Histopathology, Polytechnic University of the Marche Region (Ancona), United Hospitals, Ancona, Italy



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