A case report of primary upper urinary tract signet-ring cell carcinoma and literature review.

Upper tract urothelial carcinoma with pure non-urothelial histology is an exception but variants are present in ~ 25% of cases. Primary upper urinary tract signet -ring cell carcinoma is extremely rare.

We report the case of a 65-year-old male diagnosed primary upper urinary tract signet-ring cell carcinoma while underwent percutaneous nephrolithotomy. Radical nephroureterectomy and adjuvant chemotherapy were performed sequentially. The patient is now recovering well with a regular follow-up for more than 1 year.

The upper urinary tract malignancy often appears as a high grade, high stage tumor and has a uniformly poor prognosis, but a timely multimodal management can bring a good outcome.

BMC urology. 2020 Jun 26*** epublish ***

Zhaohua Ye, Qiwu Mi, Daosheng Luo, Zhixiong Li, Jiexin Luo

Department of Urology, Dongguan People's Hospital, Dongguan, 523000, China., Department of Urology, Dongguan People's Hospital, Dongguan, 523000, China. .