Bladder recurrence of primary upper tract urinary carcinoma following nephroureterectomy, and risk of upper urinary tract recurrence after ureteral stent positioning in patients with primary bladder cancer.

Upper tract urinary carcinoma (UTUC) and bladder cancer (BCa) share similar biological, histological and pathological characteristics. These resemblances could explain the high rate of synchronous and metachronous tumors affecting both upper urinary tract and bladder. In patients affected by primary UTUC bladder recurrence is quite common and it represents one of the major concerns during the follow-up of patients who underwent radical nephroureterectomy. Conversely, UTUC recurrence after primary non-muscular invasive BCa is a relatively rare event. Moreover, there is no clear evidence on whether the use of Double-J stenting as drainage in patients affected by BCa increases the risk of UTUC recurrence. The aim of the current study was to summarize the most recent evidence regarding the bladder recurrence after UTUC surgical treatment, and the UTUC recurrence after stent positioning in patients affected by primary BCa.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology. 2019 Jan 17 [Epub]

Francesco A Mistretta, Diego M Carrion, Sebastiano Nazzani, Juan L Vásquez, Cristian Fiori, Ottavio De Cobelli, Francesco Porpiglia, Francesco Esperto

Department of Urology, European Institute of Oncology, Milan, Italy - ., European Society of Residents in Urology (ESRU), Brussels, Belgium., Department of Urology, IRCCS San Donato Policlinic, University of Milan, Milan, Italy., Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Turin, Italy., Department of Urology, European Institute of Oncology, Milan, Italy.