Germ cell tumor in an adolescent with extensive testicular microlithiasis: Concerns regarding future management - Abstract

We report on a 14-year-old boy with bilateral testicular microlithiasis and a right-sided testicular tumor.

Tumor markers alpha-fetoprotein (AFP) and β-human chorionic gonadrotropin (β-hCG) levels were elevated and orchiectomy revealed a mixed germ cell tumor consisting of embryonal carcinoma, yolk sac tumor, choriocarcinoma, and mature teratoma. The patient had no evidence of metastatic disease. Although there is a strong association between testicular microlithiasis and testicular tumor, the pediatric literature is varying in the recommended surveillance of these patients. The literature and management of pediatric patients with testicular microlithiasis is herein reviewed.

Written by:
Cambareri GM, Reiley EA, Hensle TW.   Are you the author?
New Jersey Medical School, University of Medicine and Dentisty of New Jersey, Newark, New Jersey.

Reference: Urology. 2013 Apr 5. pii: S0090-4295(13)00193-3.
doi: 10.1016/j.urology.2013.02.011

PubMed Abstract
PMID: 23566576 Testicular Cancer Section