Two cases of cerebral sinus venous thrombosis following chemotherapy for non-seminomatous germ cell tumor - Abstract

We report on two patients with cerebral sinus venous thrombosis following chemotherapy with cisplatin, bleomycin and etoposide for non-seminomatous germ cell tumor.

Headache and neurological deficits were the leading symptoms. Cancer and cisplatin chemotherapy are well-known risk factors for thromboembolic events. The therapeutic strategy is an anticoagulant therapy. Symptoms are usually reversible within weeks under this therapy. Therefore, in patients with testicular cancer and chemotherapy who present with neurological symptoms, cerebral sinus venous thrombosis should be considered in the differential diagnosis.

Written by:
Papet C, Gutzeit A, Pless M. Are you the author?
Medical Oncology, Cantonal Hospital Winterthur, Winterthur, Switzerland.

Reference: Case Rep Oncol. 2011 Sep;4(3):555-9.
doi: 10.1159/000334850

PubMed Abstract
PMID: 22220149 Testicular Cancer Section