Testicular transposition in children before scrotal external radiotherapy.

Testicular transposition (TT) before scrotal external radiotherapy (RT) is poorly reported in children with cancer, with only rare case reports published. TT surgical techniques, dosimetric parameters, and testicular functions are retrospectively reported in 12 children, median age 12. 8 years, after scrotal RT for sarcomas. TT has low morbidity and allows a dramatic RT dose decrease in the healthy testicle. Endocrine functions seem preserved while more follow-up is needed to assess fertility. Though a rare situation, TT should be discussed in children and young adult cases when a scrotal high-dose RT is needed.

Pediatric blood & cancer. 2020 Jul 02 [Epub ahead of print]

Marielle Le Bon, Herve Lejeune, Sylvie Helfre, Stéphanie Bolle, Laetitia Padovani, Laurence Mengue, Nadege Corradini, Frédéric Hameury, Line Claude

Radiation Oncology Department, Centre Léon Bérard, Lyon, France., Reproductive Medicine Department, Hospices Civils de Lyon, Lyon, France., Radiation Oncology Department, Institut Curie, Paris, France., Radiation Oncology Department, Gustave Roussy Paris-Saclay University, Paris, France., Radiation Oncology Department, Assistance Publique des Hôpitaux de Marseille, Marseille, France., Radiation Oncology Department, Institut de Cancérologie de l'Ouest, Nantes, France., Department of Pediatric Hematology and Oncology-IHOPe, Centre Léon Bérard, Lyon, France., Department of Pediatric Surgery, Hôpital Femme Mère Enfant, Lyon, France.