Clinical features and psychological aspects of the decision-making process in stage I testicular germ cell tumors

Testicular germ cell tumors (TGCTs) are the most prevalent malignancies in young Caucasian men. Clinical stage I (CSI) TGCTs present the highest cure rate and treatment options after orchiectomy depend on histology and risk factors. Nevertheless, the management of CSI TGCTs is controversial due to the availability of multiple treatments and the lack of randomized trials. An integrated multidisciplinary approach that includes clinicians (surgeons, radiotherapists and oncologists) and psychologists is crucial to maximize the patients' compliance and must be acknowledged with appropriate tools. The aim of our work is to review the oncological and psychological aspects of the decision-making process, discussing the fundamental role of the patient involvement in the personalized management of CSI TGCTs.

Future oncology (London, England). 2018 Jun 29 [Epub ahead of print]

Caterina Condello, Pasquale Rescigno, Margaret Ottaviano, Lucia Nappi, Marianna Tortora, Sabino de Placido, Giovannella Palmieri

Department of Clinical Medicine and Surgery, Oncology Unit, University of Naples Federico II, Naples, Italy., British Columbia Cancer Agency, Vancouver Cancer Centre, British Columbia, Canada., CRTR Rare Tumors Reference Center, University of Naples Federico II, Naples, Italy.