Active Surveillance for Small Renal Masses: A Review of the Aims and Preliminary Results of the DISSRM Registry

Active surveillance is an increasingly accepted treatment modality for select patients with small renal masses. The DISSRM (delayed intervention and surveillance for small renal masses) registry is a multi-institutional, prospectively collected data repository which includes patients who select active surveillance for their small renal masses, as well as others who select immediate intervention.

Preliminary results from the registry suggest oncological equivalence of active surveillance and surgical modalities in the intermediate term. Additionally, the registry provides the first published data regarding trends in renal function among patients undergoing active surveillance. On average, these patients experience a decline in renal function, and their renal functional outcomes are superior to those of patients undergoing radical nephrectomy, but do not significantly differ from those of patients undergoing partial nephrectomy.

Current urology reports. 2016 Jan [Epub]

Matthew R Danzig, Peter Chang, Andrew A Wagner, Mohamad E Allaf, James M McKiernan, Phillip M Pierorazio

Herbert Irving Cancer Center, Columbia University College of Physicians and Surgeons, Department of Urology, New York, NY, USA. Division of Urology, Beth Israel Deaconess Medical Center, Boston, MA, USA. , Division of Urology, Beth Israel Deaconess Medical Center, Boston, MA, USA. , James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. , Herbert Irving Cancer Center, Columbia University College of Physicians and Surgeons, Department of Urology, New York, NY, USA. , James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

PubMed

E-Newsletters

Newsletter subscription

Free Daily and Weekly newsletters offered by content of interest

The fields of GU Oncology and Urology are rapidly advancing. Sign up today for articles, videos, conference highlights and abstracts from peer-review publications by disease and condition delivered to your inbox and read on the go.

Subscribe