Prognostic significance of body mass index in patients with localized renal cell carcinoma.

To investigate the relationship between the pretreatment body mass index (BMI) and the clinical outcomes in patients with localized stage I - III renal cell carcinoma (RCC) surgically treated.

From January 2000 to December 2012, 798 patients with stage I - III RCC were recruited from First Affiliated Hospital and Cancer Center of Sun Yat - Sen University. Patients were divided into two groups of BMI < 25 kg / m2 or BMI ≥ 25 kg / m2 according to the World Health Organization classifications for Asian populations. The differences in the long-term survival of these two BMI groups were analyzed.

The 5 - year failure - free survival rates for BMI < 25 kg / m2 and BMI ≥ 25 kg / m2 groups were 81.3% and 93.3%, respectively (P = 0.002), and the 5 - year overall survival rates were 82.5% and 93.8%, respectively (P = 0.003). BMI was a favored prognostic factor of overall survival and failure - free survival in a Cox regression model.

Pretreatment body mass index was an independent prognostic factor for Chinese patients surgically treated, localized stage I - III RCC.

International braz j urol : official journal of the Brazilian Society of Urology. 0000 Jan [Epub]

Chengtao Wang, Zebin Chen, Jun Dong, Bixiu Wen, Yong Fang

Department of Radiation Oncology, First Affiliated Hospital of Sun Yat - Sen University, Guangzhou, China., Department of Urology, First Affiliated Hospital of Sun Yat - Sen University, Guangzhou, China.