A multidisciplinary approach for the management of earlier stage renal cell carcinoma

Transitioning agents that are effective in advanced disease to earlier disease settings is a common pathway for drug development and a concept that has been applied to multiple agents across several tumor types. This approach is relevant in high risk renal cell carcinoma (RCC) where the relapse rate is high. Unfortunately, between 20% and 40% relapse after nephrectomy and approximately one third of patients have evidence of metastasis at initial diagnosis. These patients will proceed with focal or systemic therapy during the course of disease.

Urologic oncology. 2018 Jan [Epub]

Ana M Molina

Department of Medicine, Weill Cornell Medicine, New York, NY; Department of Urology, Weill Cornell Medicine, New York, NY; Meyer Cancer Center, Weill Cornell Medicine, New York, NY. Electronic address: .

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