[Dose adaptation of the drugs used for hematopoietic stem-cell transplantation in patients with comorbidity: Obesity, chronic renal disease or hepatopathy: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-T

In September 2016 in Lille, France, the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) organized the 7th Allogeneic Stem Cell Transplantation Clinical Practices Harmonization Workshop Series. Our work group focused on chemotherapy drug dose adaptation for hematopoietic stem cell transplantation patients presenting a comorbidity. The purpose of this workshop was to provide recommendations on chemotherapy drug dose adaptation for patient populations receiving hematopoietic stem cell transplantation who also had the following comorbidities: obesity, chronic kidney disease and hepatopathy.

Bulletin du cancer. 2017 Nov 22 [Epub ahead of print]

Nicolas Simon, Valérie Coiteux, Bénédicte Bruno, Sophie Taque, Amandine Charbonnier, Laetitia Souchet, Laure Vincent, Ibrahim Yakoub-Agha, Yves Chalandon

Université de Lille, EA 7365, GRITA, groupe de recherche sur les formes injectables et les technologies associées, 59000 Lille, France; CHU de Lille, institut de pharmacie, 59000 Lille, France., CHU de Lille, service des maladies du sang, 59000 Lille, France., CHU de Lille, service d'hématologie pédiatrique, 59000 Lille, France., CHU Anne de Bretagne, service d'hémato-oncologie pédiatrique, 2, rue Henri-Le- Guilloux, 35033 Rennes cedex 9, France., CHU, service d'hématologie clinique et de thérapie cellulaire, 80054 Amiens cedex 1, France., Groupe hospitalier Pitié-Salpêtrière, service d'hématologie clinique, 47-83, boulevard de l'Hôpital, 75013 Paris, France., CHU, département d'hématologie clinique, 191, avenue du Doyen-Gaston-Giraud, 34295 Montpellier, France., CHU de Lille, LIRIC Inserm U995, université de Lille 2, 59000 Lille, France. Electronic address: ., Hôpitaux universitaires de Genève et faculté de médecine université de Genève, service d'hématologie, 4, rue Gabrielle-Perret-Gentil, 1205 Genève, Suisse.