Establishment of Korean prostate cancer database by the Korean Urological Oncology Society

Despite the necessity, to date, no detailed database of prostate cancer, especially one that includes clinicopathological data, has been created in Korea. For that reason, the Korean Urological Oncology Society (KUOS) decided to create the Korean Prostate Cancer Database (KPCD).

The KPCD program was introduced in 2010. After considering regional distribution, a total of 20 hospitals participated in the KPCD. The Database consists of 4 domains (demographic, pretreatment, treatment, and follow-up data) and 135 variables.

In total, 7,608 men with prostate cancer between 2000 and 2010 were registered in the KPCD. The mean age at the time of diagnosis was 67.6±7.7 years. The mean PSA at diagnosis was 74.0±366.9 ng/mL, and the proportions of patients with Gleason scores of ≤6, 7, and 8-10 were 37.0%, 26.7%, and 34.2%, respectively. At diagnosis, 62.3% of the patients had localized tumors, 14.6% had regional, 12.8% had distant, and 10.4% cases were from unknown diseases. With regards to the initial treatment modality employed, 1.3% of patients were managed with active surveillance, 62.1% underwent surgery, 4.3% underwent radiotherapy, 27.1% had androgen deprivation therapy, and 5.2% underwent unknown therapies. The 5-year cancer-specific survival rate of patients in the KPCD was 98.6% in the localized stage, 94.8% in the regional stage, 74.7% in the distant stage, and 86.9% in the unknown stage.

The KUOS created a relatively successful database of patients with prostate cancer in Korea. The KPCD will continue to improve the availability of data regarding prostate cancer.

Investigative and clinical urology. 2017 Oct 25 [Epub]

Hanjong Ahn, Hyung Jin Kim, Seong Soo Jeon, Cheol Kwak, Gyung Tak Sung, Tae Gyun Kwon, Jong Yeon Park, Sung Hyun Paick

Department of Urology, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea., Department of Urology, Chonbuk National University Medical School, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea., Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Department of Urology, Seoul National University Hospital, Seoul National University School of Medicine, Seoul, Korea., Department of Urology, Dong-A University College of Medicine, Busan, Korea., Department of Urology, Kyungpook National University School of Medicine, Daegu, Korea., Department of Urology, GangNeung Asan Hospital, Ulsan University College of Medicine, Gangneung, Korea., Department of Urology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.