Prostate Cancer Local Recurrence Detected with Both (18)F-Fluciclovine and PSMA-Targeted (18)F-DCFPyL PET/CT

We present the case of a 79-year-old man with an elevated post-prostatectomy PSA level who was sequentially imaged with PET/CT using (18)F-fluciclovine followed by PSMA-targeted (18)F-DCFPyL. Although both imaging tests successfully identified the same pelvic recurrence, each radiotracer had its relative merits. This case highlights the differences between these two PET radiotracers which are increasingly being used to image men with recurrent prostate cancer.

Urology. 2017 Jun 19 [Epub ahead of print]

Michael A Gorin, Kenneth J Pienta, Martin G Pomper, Steven P Rowe

The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: ., The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.