The cumulative dose was compared with the planned dose among fourteen patients undergoing image-guided, intensity-modulated radiotherapy of the prostate bed. Moreover, we investigated the feasibility of adding dose tracking to the routine workflow for radiotherapy.
Daily cone beam computed tomography was conducted for image-guided radiotherapy, and weekly cumulative delivered doses were calculated for dose tracking. Deformable image registration was applied to map weekly dose distributions to the original treatment plan and to create a cumulative dose distribution. The dose-volume histogram (DVH) cut-off points for the rectum and bladder and the planning target volume (PTV), were used to compare the planned and cumulative delivered doses. The additional time required by the departmental staff to complete these duties was recorded.
The PTV coverage of the delivered treatment did not satisfy the expected goal for three patients (V98% >98%). In another three patients, the DVH cut-off point for the bladder was higher than the limits, while for the rectum, treatment was as expected in all cases (two patients failed both their bladder constraints and the PTV coverage). Overall, four patients did not satisfy one or more criteria at the end of their treatment.
A well-defined strategy for dose tracking assessment is feasible, would have minimal impact on the workload of a radiotherapy department, and may offer objective information to support radiation oncologists in making decisions about adaptive procedures.
Radiation oncology (London, England). 2017 Apr 28*** epublish ***
Lucia Clara Orlandini, Marianna Coppola, Christian Fulcheri, Luna Cernusco, Pei Wang, Luca Cionini
Centro Oncologico Fiorentino, Radiation Oncology Department, Via A. Ragionieri 101, 50023, Florence, Italy., Azienda Ospedaliera di Perugia, Health Physics Department, Piazzale Menghini 1, 06129, Perugia, Italy., Department of Radiation Oncology, Sichuan Cancer Hospital, No.55, the 4th Section, Renmin South Road, Chengdu, China. .