[Primary prostatic sarcoma - a rare malignancy].

Primary prostatic sarcomas are rare, reportedly comprising less than 1% of all prostate malignancies. Most patients present with lower urinary tract symptoms due to bladder outlet obstruction. Prostate-specific antigen (PSA) is typically normal. Histological confirmation and staging by a computed tomography (CT) or magnetic resonance imaging (MRI) scan of the pelvis and abdomen are essential for diagnosis and treatment planning. The differential diagnosis includes sarcomatoid prostate cancer or benign spindle cell tumors. Primary prostatic sarcomas are often aggressive and require multimodal treatment with surgery and (neo)adjuvant radiation and/or chemotherapy. The risk of local recurrence is high and the long-term prognosis is poor.

Der Urologe. Ausg. A. 2017 Mar 27 [Epub ahead of print]

A Herlemann, D Horst, M D'Anastasi, A Kretschmer, C G Stief, C Gratzke

Urologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, Marchioninistraße 15, 81377, München, Deutschland. ., Pathologisches Institut, Ludwig-Maximilians-Universität München, München, Deutschland., Institut für Klinische Radiologie, Ludwig-Maximilians-Universität München, München, Deutschland., Urologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, Marchioninistraße 15, 81377, München, Deutschland.

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