Flourodeoxyglucose positron emission tomography scan may be helpful in the case of ductal variant prostate cancer

Gallium-68 prostate specific membrane antigen ligand (Ga-68 PSMA) positron emission tomography/computed tomography (PET/CT) scanning is emerging as a useful imaging modality for the staging of suspected and known recurrent or metastatic prostate cancer and in staging of newly diagnosed higher grade prostate cancer.

However, we have observed at our institution that in some cases of the more aggressive ductal variant, Ga-68 PSMA uptake has sometimes been poor compared with prominent 18-flourodeoxyglucose (F-18 FDG) avidity seen in F-18 FDG PET/CT, which would suggest that FDG PET/CT scans are important in staging of ductal pattern prostate cancer.

Journal of medical imaging and radiation oncology. 2017 Mar 28 [Epub ahead of print]

Louise M McEwan, David Wong, John Yaxley

Wesley Medical Imaging, The Wesley Hospital, Brisbane, Queensland, Australia., Wesley Urology Clinic, The Wesley Hospital, Brisbane, Queensland, Australia.