68 Ga-PSMA Uptake by Dermatofibroma in a Patient With Prostate Cancer

Prostate-specific membrane antigen (PSMA) is a typ. 2 transmembrane protein that is highly expressed in prostate cancer cells. Ga-PSMA PET/CT imaging is a modality used to determine the extent of prostate cancer.

Various other neoplasias may also express PSMA, which appears as Ga-PSMA uptake in PET/CT imaging. A 71-year-old man with prostate cancer underwent Ga-PSMA PET/CT imaging for restaging after having an elevated prostate-specific antigen level. Subcutaneous lesions showing focal PSMA uptake were detected, one of which was excised. The histopathologic diagnosis was dermatofibroma.

Clinical nuclear medicine. 2017 Feb 24 [Epub ahead of print]

Funda Aydin, Arzu Akçal, Betül Ünal, Sema Sezgin Göksu, Firat Güngör

From the Departments of *Nuclear Medicine, †Plastic, Reconstructive and Aesthetic Surgery, ‡Pathology, and §Medical Oncology, Akdeniz University, Antalya; and ∥Department of Nuclear Medicine, Emsey Hospital, Istanbul, Turkey.