Generalized lymphadenopathy is a rare manifestation of carcinoma prostate. Here, we report a case of a 73-year-old male who presented with left supraclavicular lymphadenopathy along with hoarseness of voice and weight loss. His CT neck, chest, abdomen, and subsequently18F-FDG PET CT were suggestive of generalized lymphadenopathy with skeletal involvement. He was not having any urinary or bone symptoms. The biopsy of supraclavicular lymph node revealed metastatic adenocarcinoma, whose prostatic origin was suggested by IHC staining of PSA. The diagnosis was confirmed by prostatic biopsy along with markedly raised serum PSA. We emphasize that in men with adenocarcinoma of undetermined origin, a suspicion of prostate cancer is important for accurate diagnosis and therapeutic approach.
Indian journal of surgical oncology. 2016 Sep 11 [Epub]
Amit Sehrawat, Satyanker Gupta, Tiwari Alok
DNB Medical Oncology Resident, Dharamshila Hospital and Research Centre, Vasundhara Enclave, New Delhi, 110096 India., DNB Surgical Oncology Resident at Dharamshila Hospital and Research Centre, Vasundhra Enclave, New Delhi, 110096 India.