Metastatic Prostate Cancer Presenting as Lower Extremity Soft Tissue Mass: a Rare Case Presentation

A 69 year-old homeless African American male with prostate cancer diagnosed 2 years prior presents a large mass in the right thigh. Evaluation of the patient revealed a PSA of 9,362 ng/ml. IR biopsy of the leg mass was performed and final pathology indicated metastatic adenocarcinoma of the prostate. While metastatic prostate cancer presents most commonly in bone, lymph nodes, lungs and liver, metastatic disease presenting as a soft tissue mass is extremely rare.(1,2,3) Advent of screening with PSA has led to earlier diagnosis of lower grade disease, yet underserved populations continue to present with aggressive and morbid disease.(7).

Urology. 2016 Oct 17 [Epub ahead of print]

Paulette Cutruzzula, Daniel Edwards, David Cahn, Carmen Tong, Dana Kivlin, Laurence Belkoff