Metastatic spine tumor has become clinically important due to the availability of improved diagnostic tools and increases in survival periods in cancer patients. In spite of this interest, the burden of metastatic spine tumor on the general population has not been extensively reported.
The aim of this 2009-2011 nationwide study of adult Koreans was to describe characteristics, medical utilization, and survival rate of patients with newly diagnosed metastatic spine tumors according to the primary tumor.
Retrospsective cohort study PATIENT SAMPLE: A national health insurance database was used to identify a cohort of patients with newly diagnosed metastatic spine tumors.
To analyze characteristics, medical utilization, and survival rate of patients with newly diagnosed metastatic spine tumors according to the primary tumor.
Data for patients with metastatic spine tumors were extracted from the Korean Health Insurance Review and Assessment Service database. Data included patient age, sex, health insurance type, co-morbidities, medical cost, and hospital stay duration. Hospital stay duration and medical costs per person during one calendar year were evaluated. In addition, survival rates of metastatic spine tumor patients according to primary tumor sites were evaluated.
The incidence rate of spine metastasis increased with age, diagnosis year, and the number of comorbidities (P= <0.0001). The 6 most prevalent primary tumor sites were lung, liver & biliary, breast, colon, stomach, and prostate. Among patients with the 6 most prevalent primary tumors, total average annual medical costs, including inpatient and outpatient services, ranged from 12,734 USD (prostate origin) to 15, 556 USD (lung origin). Among patients with the 6 most prevalent primary tumors, total average annual hospital stay duration, including inpatient and outpatient services, ranged from 70.8 d (stomach origin) to 78.7 d (colon origin). Median overall survival duration in metastatic spine tumor patients was 191 d. Age, sex, comorbidities, primary tumor being in lung, liver& biliary, breast, stomach, and prostate were significantly affected survival rate.
This nationwide study were able to depict the burden of metastatic spine tumor in Korea. The metastatic spine tumor incidence rate are highest in the male 70-79 years age group. Average annual medical costs ranged from 12,734 USD to 15, 556 USD. The mean annual hospital stay duration was from 70.8 d to 78.7 d. In addition to age, sex, and comorbidities, primary tumor sites significantly affected the survival rate in metastatic spine tumor patients.
The spine journal : official journal of the North American Spine Society. 2016 Mar 10 [Epub ahead of print]
Seil Sohn, Jinhee Kim, Chun Kee Chung, Na Rae Lee, Eunjung Park, Ung-Kyu Chang, Moon Jun Sohn, Sung Hwan Kim
Department of Neurosurgery, Seoul National University College of Medicine; Neuroscience Research Institute, Seoul National University Medical Research Center; Clinical Research Institute, Seoul National University Hospital; Department of Neurosurgery, CHA Bundang Medical Center, CHA University, 59 Yatap-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 13496, South Korea., Department of Nursing, College of Medicine, Chosun University, Gwangju, Korea., Department of Neurosurgery, Seoul National University College of Medicine; Neuroscience Research Institute, Seoul National University Medical Research Center; Clinical Research Institute, Seoul National University Hospital; Department of Brain and Cognitive Sciences, Seoul National University College of Natural Sciences. National Evidence-based Healthcare Collaborating Agency, Seoul, Korea., National Evidence-based Healthcare Collaborating Agency, Seoul, Korea., Department of Neurosurgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Science., Department of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University., Department of Radiation Oncology, St. Vincent's Hospital, School of Medicine, The Catholic University of Korea.