18F-Choline PET/CT-Positive Lytic Bone Lesions in Prostate Cancer and Accidental Myeloma Detection.

F-choline PET/CT was performed for suspected prostate cancer relapse in a 67-year-old man with hip pain and a rapid rise in prostate-specific antigen values (1.1 ng/mL). PET imaging showed an area of increased F-choline bone uptake in the right ischium.

Coregistered CT images showed a lytic bone lesion. The infrequent CT appearance of a possible prostate carcinoma metastasis led to additional laboratory testing that showed a monoclonal γ-peak and to subsequent biopsy, which revealed a solitary plasmocytoma.

Clinical nuclear medicine. 2016 Jan 28 [Epub ahead of print]

Luigia Florimonte, Eva Orunesu, Massimo Castellani, Virgilio Longari, Agostino Cortelezzi

From the *Department of Nuclear Medicine; and †Division of Oncohematology, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.