High dose rate brachytherapy is a highly conformal method of radiation dose escalation for prostate cancer and one of several treatment options for men with localised disease. The large doses per fraction exploit the low alpha/beta ratio of prostate cancer cells so that biological radiation dose delivered is substantially greater than that achieved with conventional external beam delivery.
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This review article presents contemporary data on the rationale for high dose rate brachytherapy including treatment technique and future directions.
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique. 2016 Jan 22 [Epub ahead of print]
N Thiruthaneeswaran, P J Hoskin
Cancer Centre, Mount Vernon Hospital, Rickmansworth Road, Northwood, HA6 2RN, United Kingdom. , Cancer Centre, Mount Vernon Hospital, Rickmansworth Road, Northwood, HA6 2RN, United Kingdom.