Salvage prostatectomy for recurrent prostate cancer after external beam radiotherapy (EBRT) has resulted in positive outcomes; however, it is technically challenging and is associated with a number of risks.
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When a patient exhibits recurrent prostate cancer following definitive EBRT and presents with comorbidities meaning that they cannot receive a prostatectomy, it is difficult to treat due to the numerous limitations of current salvage therapies. In the present study, two cases of salvage reirradiation using helical tomotherapy for locally recurrent prostate cancer following definitive EBRT are presented. The two patients received EBRT without severe complications. Local recurrence was confirmed by serum levels of prostate-specific antigen, repeat prostate biopsy, prostate magnetic resonance imaging and a bone scan. Salvage reirradiation using helical tomotherapy was performed and resulted in promising outcomes without any complications. In conclusion, helical tomotherapy can be a safe and effective salvage treatment modality for locally recurrent prostate cancer following definitive EBRT.
Oncology letters. 2015 Jun 09 [Epub]
Sang Hyub Lee, Jinhong Jung, Sung-Goo Chang
Department of Urology, Kyung Hee University School of Medicine, Seoul 130-872, Republic of Korea. , Department of Radiation Oncology, Kyung Hee University School of Medicine, Seoul 130-872, Republic of Korea. , Department of Urology, Kyung Hee University School of Medicine, Seoul 130-872, Republic of Korea.