Metastatic Spinal Cord Compression: A Survival Score Particularly Developed for Elderly Prostate Cancer Patients

Metastatic spinal cord compression (MSCC) is an oncological emergency. Many elderly patients cannot tolerate intensive treatment and need individual approaches accounting for a patient's remaining lifetime.

The goal of the present study was to develop a survival score for elderly prostate cancer patients with MSCC.

Nine characteristics were analyzed in 243 patients: age, performance status, interval from prostate cancer diagnosis until MSCC, affected vertebrae, ambulatory status, further bone lesions, visceral metastases, time developing motor deficits, fractionation schedule.

Pre-radiotherapy ambulatory status (p

The present study identified four groups with different survival probabilities that require treatment strategies with different priorities ranging from symptom control to prolongation of life.

Anticancer research. 2015 Nov [Epub]

Dirk Rades, Antonio J Conde-Moreno, Jon Cacicedo, Barbara Segedin, Theo Veninga, Steven E Schild

Department of Radiation Oncology, University of Lübeck, Lübeck, Germany Rades.  Department of Radiation Oncology, Consorcio Hospital Provincial de Castellón, Castellón, Spain. , Department of Radiation Oncology, Cruces University Hospital, Barakaldo, Vizcaya, Spain. , Department of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia. , Department of Radiotherapy, Dr. Bernard Verbeeten Institute, Tilburg, the Netherlands. , Department of Radiation Oncology, Mayo Clinic Scottsdale, Scottsdale, AZ, U. S. A.