The diagnostic for prostate cancer is changing. To improve the detection of this cancer, urologists expect a lot from the contribution of magnetic resonance imaging (MRI). What is the role of this imaging in prostate cancer detection? This is a retrospective study, from 2011 to 2013, mono-centric and single-operator.
FREE DAILY AND WEEKLY NEWSLETTERS OFFERED BY CONTENT OF INTEREST
Did you find this article relevant? Subscribe to UroToday-GUOncToday!
The fields of GU Oncology and Urology are advancing rapidly including new treatments, enrolling clinical trials, screening and surveillance recommendations along with updated guidelines. Join us as one of our subscribers who rely on UroToday as their must-read source for the latest news and data on drugs. Sign up today for blogs, video conversations, conference highlights and abstracts from peer-review publications by disease and condition delivered to your inbox and read on the go.
Of the 464 needle biopsy of the prostate (BP), we excluded those with PSA>20ng/mL or digital rectal examination (DRE)>T3. The remaining 430 BP were submitted or not to a 1. 5 tesla MRI with pelvic antenna. The primary aim is the overall detection of prostate cancer. Secondary aim was the detection rate during the first series of BP and repeat BP, between the two groups in the MRI group. MRI and MRI without populations are comparable for age (63. 3 vs 64. 6), PSA (6. 10 vs 6. 13), DRE>T1c, prostate volume (55. 4 cm(3) vs 51. 7 cm(3)). There is no significant difference in overall detection between the two groups (P=0. 12). There is no significant difference in cancer detection between the first BP (P=0. 13) and the repeat BP (P=0. 07). There is a significant difference in the early detection of BP MRI group (P=0. 03) but not for the BP repeat MRI group (P=0. 07). For 108 BP iterative MRI group, there were 67 BP targeted "mentally" with MRI: 18 cancers were detected, making a 25% detection rate. This study helps to highlight the value of MRI in the early rounds of BP but we can ask the value of this imaging during repeat biopsies. Targeted biopsies "mentally" do not have the expected detection sensitivity and seems to require a three-dimensional reconstruction to be more effective.
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 2015 Sep 29 [Epub ahead of print]
S Bassard, J-L Mege
Service urologie, CHU de Dijon, 14, rue Paul-Gaffarel, 21079 Dijon, France. Hôpital privé Ste-Marie, 4, allée St-Jean-des-Vignes, 71100 Chalon-sur-Saône, France.