Various strategies have been used to treat patients with nonpalpable prostate cancer (T1c). As one of the treatments for this stage, a radical prostatectomy was performed and the outcomes were evaluated.
Between 1993 and 2002, 117 patients with T1c received a radical prostatectomy and their follow-up were examined by the end of 2013 Patients were classified according to risk groups using prostate-specific antigen (PSA) and Gleasson score, and outcomes of respective groups were compared
Approximately 60% of patients were in low risk group, and the remaining patients were grouped into the intermediate or high risks in half In 22% insignificant cancer was detected Biochemical failure occurred in 14% One patient exhibited bone metastasis, but no deaths from prostate cancer ware observed The five and ten year overall survival rates were 92% and 75%, respectively, and the biochemical failure-free survival rates were 92% and 89%, respectively No different outcomes were observed for the different risk groups in the overall and biochemical failure-free survival rates T1c tumors contain a certain range of various stages of tumors, but most patients experienced favorable outcomes
Radical prostatectomy as monotherapy is one of the treatment option for T1c prostate cancer patients, who have a long life span and belong to intermediate or high risk groups
Prostate international 2015 Feb 10 [Epub]
Yoshiyasu Amiya, Makoto Sasaki, Takayuki Shima, Yuusuke Tomiyama, Noriyuki Suzuki, Shino Murakami, Hiroomi Nakatsu, Jun Shimazaki
Department of Urology, Asahi General Hospital, Asahi, Japan , Department of Urology, Asahi General Hospital, Asahi, Japan , Department of Urology, Asahi General Hospital, Asahi, Japan , Department of Urology, Asahi General Hospital, Asahi, Japan , Department of Urology, Asahi General Hospital, Asahi, Japan , Department of Urology, Asahi General Hospital, Asahi, Japan , Department of Urology, Asahi General Hospital, Asahi, Japan , Department of Urology, Graduate School of Medicine, Chiba University, Chiba, Japan