Applying precision medicine to the active surveillance of prostate cancer.

The recent introduction of a variety of molecular tests will potentially reshape the care of patients with prostate cancer.

These tests may make more accurate management decisions possible for those patients who have been "overdiagnosed" with biologically indolent disease, which represents an exceptionally small mortality risk. There is a wide range of possible applications of these tests to different clinical scenarios in patient populations managed with active surveillance.

Cancer 2015. © 2015 American Cancer Society.

Cancer. 2015 Jul 6. doi: 10.1002/cncr.29496. [Epub ahead of print]

Reichard CA1, Stephenson AJ1, Klein EA1.

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.