The role of MRI in active surveillance for prostate cancer - Abstract

Approximately one in seven American men will be diagnosed with prostate cancer during his lifetime, and at least 50% of newly diagnosed patients will present with low-risk disease.

In the last decade, the decision-making paradigm for management has shifted due to high rates of disease detection and overtreatment, attributed to prostate-specific antigen screening, with more men deferring definitive treatment for active surveillance. The advent of multiparametric magnetic resonance imaging (MP-MRI) and MRI/ transrectal ultrasound-guided fusion-guided prostate biopsy has refined the process of diagnosis, identifying patients with clinically-significant cancer and larger disease burden who would most likely benefit from intervention. In parallel, the utilization of MP-MRI in the surveillance of low-grade, low-volume disease is on the rise, reflecting support in a growing body of literature. The aim of this review is to appraise and summarize the data evaluating the role of magnetic resonance imaging in active surveillance for prostate cancer.

Written by:
Fascelli M, George AK, Frye T, Turkbey B, Choyke PL, Pinto PA.   Are you the author?
Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, MSC 1210, 10 Center Drive, Bethesda, MD, 20892-1210, USA.

Reference: Curr Urol Rep. 2015 Jun;16(6):42.
doi: 10.1007/s11934-015-0507-9

PubMed Abstract
PMID: 26017850 Prostate Cancer Section