OBJECTIVE: To investigate the correlation between the parameters of prostate cancer (PCa) at contrast-enhanced ultrasound (CEUS) with PCa risk.
METHODS: 84 Patients (68 ± 8 years; range, 33-79 years) who had undergone CEUS were included. All the images were offline analyzed. Parameters (maximum intensity (IMAX), rise time (RT), time to peak (TTP) and mean transit time (mTT)) were recorded and compared with PSA level, Gleason score, clinical stages and PCa risk.
RESULTS: Age was correlated significantly with PCa risk. RT and mTT of outer gland were associated with PCa risk. No significant correlation was found between PSA and CEUS enhancement parameters. Furthermore, with the exception of IMAX of inner gland and IMAX of outer gland, there were no significant differences of enhancement parameters in Gleason score groups and clinical stages groups.
CONCLUSION: The enhancement parameters of PCa at CEUS may be used to predict PCa risk. And it is helpful for the choice of therapeutic options.
Written by:
Xu G, Wu J, Yao MH, Yao XD, Peng B, Wei Q, Xu HX, Wu R. Are you the author?
Department of Medical Ultrasound, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China; Department of Urology, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China; Department of Pathology, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China; State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences Shanghai 200050, China.
Reference: Int J Clin Exp Med. 2015 Feb 15;8(2):2562-9.
PubMed Abstract
PMID: 25932202