Extended pelvic lymph node dissection for clinically localized prostate cancer: A West Australian experience - Abstract

BACKGROUND: The role and type of pelvic lymph node dissection for clinically localized prostate cancer is controversial in Australia.

Our study aims to determine the incidence of pelvic lymph node involvement and the complication rate of extended lymphadenectomy in a group of West Australian patients who underwent a robotic assisted radical prostatectomy plus extended pelvic lymph node dissection.

METHOD: Forty-nine patients underwent a robotic assisted radical prostatectomy with extended pelvic lymph node dissection between 2008 and 2012 by a single private urological surgeon. The inclusion criteria for the extended lymph node dissection were clinical localized, intermediate and high-risk prostate cancer based on preoperative D'Amico classification.

RESULTS: Of the 49 patients, eight patients had positive nodes giving a nodal positivity rate of 16.33%. Six patients had a complication giving a total complication rate of 12.24%. Three of these complications have been attributed to the nodal dissection, thus giving an extended pelvic lymph node dissection complication rate of 6.12%.

CONCLUSION: Rates of nodal involvement in our West Australian cohort are in keeping with those published in the literature. Extended pelvic lymph node dissection can be performed with an acceptable complication rate. Further research is required to investigate the therapeutic role of pelvic lymph node dissection.

Written by:
Picardo A, Vivian J.   Are you the author?
Urology Department, St John of God Hospital, Perth, Western Australia, Australia.

Reference: ANZ J Surg. 2015 Mar 17. Epub ahead of print.
doi: 10.1111/ans.13035

 
PubMed Abstract
PMID: 25780994

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