Information of prostate biopsy positive core: Does it affect MR detection of prostate cancer on using 3T-MRI? - Abstract

OBJECTIVE: We assessed which information from a prostate biopsy had the strongest relationship with prostate cancer detection by 3T-MRI.

MATERIALS AND METHODS: Sixty-one consecutive patients with biopsy-proven prostate cancer who underwent 3T-MRI before biopsy were enrolled in this retrospective study. Two radiologists independently reviewed T2-weighted and diffusion-weighted images. When the cancer lesions were revealed by biopsy and MRI depicted them at corresponding sites, we classified these lesions as MRI-detectable cancer. If the cancer lesions were revealed by biopsy, but any cancers had not been detected, we classified these lesions as MRI-undetectable cancer. We compared the Gleason score (GS), cancer ratio (CaR) and cancer length (CaL) from core biopsies between the two groups.

THE RESULTS: GS, CaR and CaL differed significantly between the MRI-detectable group (N = 70), and the MRI-undetectable group (N = 73). 3T-MRI could detect cancer cores with a sensitivity of 90.5 % in cores with CaR ≥ 60 %, and with a sensitivity of 81.8 % in those with CaL ≥ 5 mm. Receiver operating characteristic analysis showed that CaR (P = 0.006) and CaL (P = 0.010) significantly associated with the prostate cancer detection using MRI rather than GS.

CONCLUSION: CaR and CaL from the core biopsies showed a stronger relationship to detection of the prostate cancer on 3T-MRI than the GS did.

Written by:
Yoshida R, Kaji Y, Tamaki Y, Katsube T, Kitagaki H, Kanbara T, Kamai T.   Are you the author?
Department of Radiology, Faculty of Medicine, Shimane University, 89-1, Enya-cho, Izumo, Shimane, 693-8501, Japan.

Reference: Jpn J Radiol. 2015 Mar 12. Epub ahead of print.
doi: 10.1007/s11604-015-0407-4

 
PubMed Abstract
PMID: 25761402

UroToday.com Prostate Cancer Section

E-Newsletters

Newsletter subscription

Free Daily and Weekly newsletters offered by content of interest

The fields of GU Oncology and Urology are rapidly advancing. Sign up today for articles, videos, conference highlights and abstracts from peer-review publications by disease and condition delivered to your inbox and read on the go.

Subscribe