Comparative histopathological characterization of prostate cancer in Saudi patients by conventional and 2005 ISUP modified Gleason systems - Abstract

BACKGROUND: The aim of this study was to compare the characterization of prostate cancer using the conventional and 2005 ISUP modified Gleason systems.

MATERIALS AND METHODS: The study employed samples from 40 prostate cancer patients with resection, biopsy and RP materials. The majority of cases (95%) comprised adenocarcinoma of the prostate with a modified combined Gleason score of 7 in 20 of the cases (50%).

RESULTS: Upgrading of Gleason scores to a score of 7 occurred in more than 45% of the cases.

CONCLUSION: The study successfully showed that by the use of the 2005 ISUP modified Gleason system, score 6 cancers decreased from 25% to 17.5% of cases, whereas score 7 cancers increased from 45% to 50%.

Written by:
Al Suhaibani ES, Kizilbash NA, Al Beladi F.   Are you the author?
Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.  

Reference: Asian Pac J Cancer Prev. 2014;15(24):10923-6.

PubMed Abstract
PMID: 25605202 Prostate Cancer Section