Impact of comorbidities on prostate cancer stage at diagnosis in Florida - Abstract

To examine the association of major types of comorbidity with late-stage prostate cancer, a random sample of 11,083 men diagnosed with prostate cancer during 2002-2007 was taken from the Florida Cancer Data System.

Individual-level covariates included demographics, primary insurance payer, and comorbidity following the Elixhauser Index. Socioeconomic variables were extracted from Census 2000 data and merged to the individual level data. Provider-to-case ratio at county level was alsocomputed. Multilevel logistic regression was used to assess associations between these factors and late-stage diagnosis of prostate cancer. Higher odds of late-stage diagnosis was significantly related to presence of comorbidities, being unmarried, current smoker, uninsured, and diagnosed in not-for-profit hospitals. The study reported that the presence of certain comorbidities, specifically 10 out of the 45, was associated with late-stage prostate cancer diagnosis. Eight out of 10 significant comorbid conditions were associated with greater risk of being diagnosed at late-stage prostate cancer. On the other hand, men who had chronic pulmonary disease, and solid tumor without metastasis, were less likely to be diagnosed with late-stage prostate cancer. Late-stage diagnosis was associated with comorbidity, which is often associated with increased health care utilization. The association of comorbidity with late-stage prostate cancer diagnosis suggests that individuals with significant comorbidity should be offered routine screening for prostate cancer rather than focusing only on managing symptomatic health problems.

Written by:
Xiao H, Tan F, Goovaerts P, Adunlin G, Ali AA, Gwede CK, Huang Y.   Are you the author?
Florida A&M University, Tallahassee, FL, USA; Indiana University-Purdue University Indianapolis, IN, USA; BioMedware Inc., Ann Arbor, MI, USA; Florida A&M University, Tallahassee, FL, USA; University of South Florida, Tampa, FL, USA; Centers for Disease Control and Prevention Foundation, Atlanta, GA.  

Reference: Am J Mens Health. 2014 Dec 26. pii: 1557988314564593.
doi: 10.1177/1557988314564593


PubMed Abstract
PMID: 25542838

UroToday.com Prostate Cancer Section

E-Newsletters

Newsletter subscription

Free Daily and Weekly newsletters offered by content of interest

The fields of GU Oncology and Urology are rapidly advancing. Sign up today for articles, videos, conference highlights and abstracts from peer-review publications by disease and condition delivered to your inbox and read on the go.

Subscribe