Bone health management in men undergoing ADT: Examining enablers and barriers to care - Abstract

The study determined prostate cancer specialists' knowledge and concordance to guidelines regarding the diagnosis, management, and prevention of androgen deprivation therapy-induced osteoporosis.

Despite high knowledge regarding bone health, most respondents did not routinely measure bone mineral density or use fracture risk assessment tools, suggesting a significant gap in the screening/monitoring of bone health.

INTRODUCTION: The purpose of this study was to determine prostate cancer specialists' knowledge, practices, self-perceived competencies and barriers to providing guideline-concordant care in the diagnosis, prevention, and management of androgen deprivation therapy (ADT)-induced osteoporosis (OP).

METHODS: A number of 73 Canadian radiation oncologists and 83 urologists completed questionnaires assessing (i) knowledge regarding OP and consensus guidelines for bone health management in men receiving ADT, (ii) self-assessed competencies regarding bone health management, (iii) current practices regarding OP prevention and management, and (iv) self-perceived barriers to providing guideline-concordant care.

RESULTS: The majority of respondents were able to correctly identify the guideline-concordant frequency of repeat dual-energy X-Ray absorptiometry (DXA) scans (76.3 %), vitamin D (70.3 %), and calcium (53.2 %) intake and that bisphosphonates/denosumab should always be considered for patients with a history of one low-trauma fracture (57.6 %). Just under 1/3 (32.5 %) reported routinely measuring bone mineral density (BMD) prior to starting ADT and routinely measuring BMD 1-2 years following the initiation of ADT (36.6 %). Only 4.6 % of respondents routinely used a validated fracture risk assessment tool. Lowest self-assessed competency levels were reported in providing self-management education to patients to foster the uptake of healthy bone behaviors (HBBs) and managing patients who present with or develop osteopenia and OP. The most significant barriers to providing OP prevention and management were lack of time and lack of supporting structures.

CONCLUSIONS: Despite high knowledge about appropriate bone health care among prostate cancer specialists, there remain significant gaps in screening and monitoring of bone health, suggesting the need to develop innovative strategies to overcome barriers to implementation.

Written by:
Damji AN, Bies K, Alibhai SM, Jones JM.   Are you the author?
Undergraduate Medical Education Program, University of Toronto, Toronto, Canada.

Reference: Osteoporos Int. 2014 Dec 20. Epub ahead of print.
doi: 10.1007/s00198-014-2997-6

PubMed Abstract
PMID: 25526712 Prostate Cancer Section


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