Informed decision making among first-degree relatives of prostate cancer survivors: A pilot randomized trial - Abstract

BACKGROUND: First degree relatives (FDRs) of men diagnosed with prostate cancer (PCa) are at increased risk for developing the disease, due in part to multiple concurrent risk factors.

There is a lack of innovative targeted decision aids to help FDRs make an informed decision about whether or not to undergo PCa screening.

PURPOSE: This randomized pilot trial evaluated the efficacy of a targeted PCa screening decision aid in unaffected FDRs of PCa survivors.

METHODS: Seventy-eight Black and White FDRs were randomized to one of two decision aid groups; 39 to a FDR-targeted decision aid and 39 to a general decision aid. The targeted decision aid group received a general PCa decision aid booklet plus a newly developed decision aid DVD targeted specifically for FDRs. PCa screening decision outcomes included knowledge, decisional conflict, distress, and satisfaction with screening decision. Outcomes were assessed at baseline and 4 weeks after baseline.

RESULTS: There were no differences by intervention group for knowledge, decisional conflict, distress, or satisfaction with screening decision (p>0.05). However, men in both groups had significant increases in knowledge and decreases in decisional conflict (p< 0.001). These changes were most pronounced (p< 0.05) for younger men compared to older men.

CONCLUSION: Results suggest that general and targeted information can play an important role in increasing knowledge and decreasing decisional conflict among FDRs. Additional research is needed to identify subgroups of men who benefit the most and better understand the outcomes of a screening decision aid among diverse samples of FDRs.

Written by:
Davis SN, Sutton SK, Vadaparampil ST, Meade CD, Rivers BM, Patel MV, Torres-Roca JF, Heysek RV, Spiess P, Pow-Sang J, Jacobsen PB, Gwede CK.   Are you the author?
Institution(s): See publishing journal.

Reference: Contemp Clin Trials. 2014 Nov;39(2):327-34.
doi: 10.1016/j.cct.2014.10.007

PubMed Abstract
PMID: 25465497 Prostate Cancer Section


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