Mixed adenocarcinoma and neuroendocrine prostate cancer: A case report - Abstract

BACKGROUND: Neuroendocrine prostate cancer is rare but lethal.

It is one of the most common extra pulmonary manifestations of small cell cancer.

CASE PRESENTATION: Here we present a case report of a 53-year-old male who presents with a mixed adenocarcinoma and neuroendocrine prostate tumor on a background of previously normal prostate-specific antigen (PSA). His initial symptoms prior to diagnosis included decreased urine output and acute kidney injury (AKI).

CONCLUSION: Neuroendocrine tumor does not elevate the PSA level and hence is often a late finding with a poor prognosis. Special staining on histopathogy is required to reveal this diagnosis.

Written by:
Hingorani R, Young J, Alweis R.   Are you the author?
Department of Medicine, Reading Health System, West Reading, PA, USA; Jefferson Medical College, Philadelphia, PA, USA.

Reference: J Community Hosp Intern Med Perspect. 2014 Nov 25;4(5):25176.
doi: 10.3402/jchimp.v4.25176

PubMed Abstract
PMID: 25432647

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