Dose-escalated radiation therapy for localized prostate cancer improves disease control but is also associated with worse rectal toxicity.
A spacer placed between the prostate and rectum can be used to displace the anterior rectal wall outside of the high-dose radiation regions and potentially minimize radiation-induced rectal toxicity. This systematic review focuses on the published data regarding the different types of commercially available prostate-rectum spacers. Dosimetric results and preliminary clinical data using prostate-rectum spacers in patients with localized prostate cancer treated by curative radiation therapy are compared and discussed.
Mok G, Benz E, Vallee JP, Miralbell R, Zilli T. Are you the author?
Department of Radiation Oncology, Geneva University Hospital, Geneva, Switzerland; Department of Radiation Oncology, Centre Intégré de Cancérologie de Laval, Centre de Santé et de Services Sociaux de Laval, Laval, Québec, Canada; Department of Radiology, Radiation Oncology, and Nuclear Medicine, Centre Hospitalier Universitaire de Montréal, Montréal, Québec, Canada; Department of Radiology, Geneva University Hospital, Geneva, Switzerland.
Reference: Int J Radiat Oncol Biol Phys. 2014 Oct 1;90(2):278-288.