Men who undergo long-term androgen deprivation therapy (ADT) may experience systemic side effects similar to the classical metabolic syndrome.
Exercise is a potential strategy for offsetting the adverse effects of ADT among patients with prostate cancer, resulting in improved muscular resistance and positive outcomes on body size and composition. Fitness (aerobic capacity), fatigue and certain quality of life (QOL) outcomes may also improve in response to a regular exercise regimen. Caution and cardiovascular screening are merited given the elderly population with this disease.
Segal R. Are you the author?
Medical Oncologist, Regional Cancer Center, Medical Lead, Breast Disease Site, Head Survivorship Program, Associate Professor of Medicine, University of Ottawa, The Ottawa Hospital Regional Cancer Program, Ottawa, ON.
Reference: Can Urol Assoc J. 2014 Jul;8(7-8 Suppl 5):S162-3.