Treatment of localized prostate cancer by vascular-targeted photodynamic therapy with WST11 - Abstract

Focal therapies are new options for the treatment of localized prostate cancer.

Vascular-targeted photodynamic therapy (VTP) with WST11 is one of these options. The aim of this treatment is to destroy a targeted area of the prostate by the associated action of the WST11 drug, light exposure and oxygen. The procedure is performed under general anesthesia. Fibers are introduced trans-perineally in the prostate by ultrasound guidance. The injection of WST11 is then performed with light illumination of the specific targeted area. Current data report 83% negative biopsies 6 months after treatment with good tolerance of the treatment. However, VTP still needs to be evaluated.

Written by:
Lebdai S, Martin F, Bigot P, Azzouzi AR.   Are you the author?
Service d'urologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France.  

Reference: Prog Urol. 2014 Sep 3. pii: S1166-7087(14)00212-7.
doi: 10.1016/j.purol.2014.08.002

PubMed Abstract
PMID: 25195031

Article in French. Prostate Cancer Section