BACKGROUND: A potential risk factor for prostate cancer is occupational physical activity.
FREE DAILY AND WEEKLY NEWSLETTERS OFFERED BY CONTENT OF INTEREST
Did you find this article relevant? Subscribe to UroToday-GUOncToday!
The fields of GU Oncology and Urology are advancing rapidly including new treatments, enrolling clinical trials, screening and surveillance recommendations along with updated guidelines. Join us as one of our subscribers who rely on UroToday as their must-read source for the latest news and data on drugs. Sign up today for blogs, video conversations, conference highlights and abstracts from peer-review publications by disease and condition delivered to your inbox and read on the go.
The occupational aetiology of prostate cancer remains unclear. The purpose of this research was to examine associations between the level of exposure to various measures of physical activity at work and the risk of Prostate Cancer.
METHODS: Using the Finnish Job Exposure Matrix and the occupational history of 1,436 cases and 1,349 matched controls from an Australian case control study; we investigated five related exposure variables considered to be risk factors by comparing odds ratios.
RESULTS: Modestly increasing odds ratios were detected with increasing levels of workload but there was no difference in this trend between moderate and high grade tumours. In regard to occupational physical workload no statistically significant association was observed overall but an increasing trend with level of exposure was observed for high grade compared with moderate grade tumours.
CONCLUSION: Both workload and physical workload merit further investigation, particularly for the latter in relation to grade of tumour.
Doolan GW, Benke G, Giles GG, Severi G, Kauppinen T. Are you the author?
Department of Epidemiology & Preventive Medicine, Monash University, The Alfred Centre, The Alfred, Commercial Road, Melbourne, Victoria 3004, Australia.
Reference: Environ Health. 2014 Aug 7;13:64.