GU Cancers Symposium 2013 - Randomized phase II trial evaluating the optimal sequencing of sipuleucel-T and androgen deprivation therapy (ADT) in patients with biochemically recurrent prostate cancer: Immune results, by Emmanuel S. Antonarakis, MD, et al

ORLANDO, FL, USA ( - Sipuleucel-T is an autologous cellular immunotherapy that targets prostatic acid phosphatase (PAP) and is FDA-approved for the treatment of men with asymptomatic or minimally symptomatic metastatic castration-resistant prostate cancer (mCRPC). Optimal sequencing of ADT and sipuleucel-T to maximize immune and clinical responses is unknown.

Here, we report interim data from a phase 2 trial evaluating the sequencing of sipuleucel-T and ADT by examining immune parameters in patients with BRPC at high risk for metastases...Click here to enlarge and view the poster.


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                                (Click thumbnail to enlarge poster)


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Presented by Emmanuel S. Antonarakis,1 Adam S. Kibel,2 Robert C. Tyler,3 Candice McCoy,3 Yang Wang,3 Nadeem A. Sheikh,3 and Charles G. Drake1 at the 2013 Genitourinary Cancers Symposium - February 14 - 16, 2013 - Rosen Shingle Creek - Orlando, Florida USA

1Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD; 2Dana-Farber Cancer Institute, Boston, MA; 3Dendreon Corporation, Seattle, WA

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