We present a case of a previously healthy and active 64-year-old man who experienced a rapid neuropsychiatric decline.
All tests for metabolic causes, neuroinfection, intracranial infarction or tumor were negative. By the means of magnetic resonance imaging, electroencephalography and the anti-Hu antibody test the patient was diagnosed with paraneoplastic limbic encephalitis related to prostate cancer. The patient died within 6 months. We review the literature on prostate cancer-related paraneoplastic limbic encephalitis. High-risk prostate cancer can trigger paraneoplastic limbic encephalitis, a rapidly progressive neurological syndrome with a bad prognosis.
Written by:
Jakobsen JK, Zakharia ER, Boysen AK, Andersen H, Schlesinger FE, Lund L. Are you the author?
Department of Urology, Viborg Hospital, Viborg, Denmark.
Reference: Int J Urol. 2012 Nov 27. Epub ahead of print.
doi: 10.1111/iju.12030
PubMed Abstract
PMID: 23186204
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