Predicting erectile function outcome in men after radical prostatectomy for prostate cancer - Abstract

Institute of Naval Medicine, Alverstoke St Peter`s Andrology Centre, London, UK.

Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI; Section of Robotic and Laparoscopic Surgery, University of Rochester, Rochester, NY, USA; Department of Urology and Endocrine Surgery, University Hospital North Norway, Tromsoe, Norway.



To identify the reported rates of potency after prostatectomy in the recent literature for men without preoperative erectile dysfunction (ED) and to develop a statistical model for predicting the expected potency after prostatectomy.

A Medline search was conducted with the keywords 'potency' and 'prostatectomy' from 2003 to 2009. In total, 33 studies in the English language reporting pre- and postoperative erectile function were identified.  Data from studies reporting outcome after open, laparoscopic and robot-assisted prostatectomy were analyzed separately.  Only data obtained from potent men before surgery were included in the analysis.

In potent men before surgery, the main predictors of post-treatment erectile function are age and time after treatment.  The cumulative range of potency rates at 48 months for all ages (45-75 years) was 49-74% for open, 58-74% for laparoscopic and 60-100% for robotic prostatectomy. The predicted outcome differs by type of operation and patient age.

Men aged < 60 years have a significant likelihood of regaining erectile function after radical prostatectomy. The reported statistical model provides a reliable estimation of erectile function outcome after prostatectomy for men with localized prostate cancer and intact erectile function.

Written by:
Kilminster S, Müller S, Menon M, Joseph JV, Ralph DJ, Patel HR.   Are you the author?

Reference: BJU Int. 2011 Dec 19. Epub ahead of print.
doi: 10.1111/j.1464-410X.2011.10757.x

PubMed Abstract
PMID: 22182202 Prostate Cancer Section