Active surveillance criteria for prostate cancer: Can they be applied to Japanese patients? - Abstract

Departments of Urology Pathology, Yokohama Rosai Hospital, Yokohama, Kanagawa Japan.

Department of Urology, Toho University Sakura Medical Center, Sakura, Chiba, Japan.

 

 

Prostate-specific antigen screening has significantly increased the percentage of men who are diagnosed with low-risk prostate cancer. All men undergoing retropubic radical prostatectomy for primary treatment of prostate cancer from April 2004 to September 2010 in our hospital were examined in order to determine whether active surveillance criteria could be applied to Japanese men. From pathological data of prostate biopsies, whether these men met five published criteria for active surveillance (Johns Hopkins Medical Institution, Prostate Cancer Research International: Active Surveillance Study, University of California, San Francisco, Toronto and Kakehi criteria) was evaluated. Men who met any of the criteria had a statistically significant lower extracapsular extension rate and organ-confinement rate. From the view of the possibility of Gleason upgrading and organ-confinement rate, the Johns Hopkins Medical Institution and Prostate Cancer Research International: Active Surveillance Study criteria showed to be appropriate for Japanese patients. However, the present study had limitations of selection bias and a limited number of cases.

Written by:
Goto Y, Nozumi K, Miyazaki K, Matsumoto A, Inoue A, Kito H, Hasegawa N, Nagata M, Kakuta Y, Suzuki H, Yamaguchi K.   Are you the author?

Reference: Int J Urol. 2011 Nov 9. Epub ahead of print.
doi: 10.1111/j.1442-2042.2011.02900.x

PubMed Abstract
PMID: 22070372

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