Metastatic prostate adenocarcinoma invading an atypical meningioma - Abstract

Department of Neurosurgery, The Royal Melbourne Hospital, Grattan Street, Parkville, Victoria 3050, Australia.


Although prostate adenocarcinoma is the most commonly diagnosed cancer in men, intracranial metastases are rare. We describe a 72-year-old patient with known metastatic prostate cancer, presenting with a dural-based parafalcine lesion on radiological imaging, following a seizure. Total macroscopic excision of the lesion was achieved at surgery, with histopathology confirming prostate adenocarcinoma embedded in an atypical (World Health Organization Grade II) meningioma, fulfilling all the criteria for true tumour-to-tumour metastasis. To our knowledge, this is the first report of prostate cancer metastasising to an atypical meningioma.

Written by:
Mitchell RA, Dimou J, Tsui A, Kavar B.   Are you the author?

Reference: J Clin Neurosci. 2011 Oct 12. Epub ahead of print.
doi: 10.1016/j.jocn.2011.03.019

PubMed Abstract
PMID: 22000836 Prostate Cancer Section