Prostatic adenocarcinoma metastatic to pleomorphic liposarcoma, a "collision phenomenon": Report of a case with review of pelvic collision tumors - Abstract

Department of Pathology, University of Pittsburgh Medical Center, A615, Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA.


"Collision tumor" is an uncommon phenomenon characterized by coexistence of two completely distinct and independent tumors at the same site. Collision tumors have been reported in different sites in the body; however, these are particularly uncommon in the pelvic cavity. A 70-year-old man, with prior history of urothelial and prostate cancer, presented with a large pelvic mass detected on imaging studies. Pathological examination revealed a large liposarcoma with prostatic carcinoma embedded in it. Immunohistochemistry and florescence in situ hybridization studies were performed to reach to a conclusive diagnosis. To the best of our knowledge, this is the second case reported till date. We present the challenges encountered in the diagnosis of this case and review of pelvic collision tumors.

Written by:
Roy S, Hrebinko RL, Cieply KM, Parwani AV, Rao UN.   Are you the author?

Reference: Patholog Res Int. 2011;2011:173541.
doi: 10.4061/2011/173541

PubMed Abstract
PMID: 21904691 Prostate Cancer Section