Department of Urology, University of Michigan Medical Center, 1500 East Medical Center Drive , Ann Arbor, MI 48109-0330, USA.Eisenhower Wellness Institute, Eisenhower Medical Center, Rancho Mirage, CA, USA.
Support for a prescription statin clinical trial for the prevention or treatment of prostate cancer has been lacking, although recent data have provoked interest in such a study. The authors have initiated a pilot trial of red yeast rice (RYR) extract and prostate cancer. RYR significantly reduces low-density lipoprotein and is an option for statin-intolerant patients. RYR appears to be an adequate proxy for some statins as long as quality control is monitored. The REALITY (REduction in Active surveillance Lipid Indices Through Yeast of red rice) trial will be conducted in Toronto, Canada.
Moyad MA, Klotz LH. Are you the author?
Reference: Urol Clin North Am. 2011 Aug;38(3):325-31.