The Urological Diseases Research Center, Boston, MA, USA.
Enders Research Laboratories, Department of Orthopaedic Surgery, Children's Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
Research into the role of cholesterol and prostate disease has been ongoing for many years, but our mechanistic and translational understanding is still poor. Recent evidence indicates that cholesterol-lowering drugs reduce the risk of aggressive prostate cancer. This article reviews the literature on the relationship between circulating cholesterol and prostate cancer. The data strongly point to hypercholesterolemia as a risk factor for prostate cancer progression and suggest clinical opportunities for the use of cholesterol-lowering therapies to alter disease course.
Written by:
Solomon KR, Freeman MR. Are you the author?
Reference: Urol Clin North Am. 2011 Aug;38(3):243-59.
doi: 10.1016/j.ucl.2011.04.001
PubMed Abstract
PMID: 21798387
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