AUA 2011 - Potency outcomes in patients who had multiple biopsies before radical prostatectomy for the treatment of localized prostate cancer - Session Highlights

WASHINGTON, DC USA ( - What is the effect of numerous prostate biopsies on eventual erectile function following radical prostatectomy this group asked?

Maybe not so good, they found. They hypothesized that multiple biopsies might cause scarring of tissue and difficulty in dissection during surgery which results in poorer surgical and functional outcomes. They retrospectively analyzed the data of 366 consecutive patients who underwent RALP between May 2009 and December 2009 at a single institution by a single surgeon. They were grouped into those who had single biopsy (n=316) and multiple biopsies (n=50) prior to the operation. Using modified D’Amico risk criteria patients were risk stratified into low-, intermediate- and high-risk groups. Next they excluded intermediate and high-risk cases, those with a pre-operative IIEF <60, and those that underwent non-nerve sparing. The control group was then matched with the study group. This left a total of 69 matched patients, 22 in the multiple biopsy group and 47 in single biopsy group.

They key finding was that at 3 months 55.0% and 44.1% of patients were potent in the single biopsy and multiple biopsy groups respectively (p<0.05); at 6 months 84% and 75% patients were potent in the single biopsy and multiple biopsy groups respectively (p<0.05). In terms of continence function the two groups did not differ significantly.



Presented by Swathi Roy, et al. at the American Urological Association (AUA) Annual Meeting - May 14 - 19, 2011 - Walter E. Washington Convention Center, Washington, DC USA

Reported for UroToday by Christopher P. Evans, MD, FACS, Professor and Chairman, Department of Urology, University of California, Davis, School of Medicine.


The opinions expressed in this article are those of the Contributing Editor and do not necessarily reflect the viewpoints of the American Urological Association.



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